SCHEMBL8980273

SCHEMBL8980273

COc1ccc2scnc2c1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA7 P43166 2/20 0.47
CA9 Q16790 2/20 0.47
CA14 Q9ULX7 2/20 0.47
ECE1 P42892 2/20 0.39
KDM4E B2RXH2 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MALT1 Q9UDY8 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
TPMT P51580 1/20 0.38
RAB9A P51151 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
NPC1 O15118 1/20 0.37
HKDC1 Q2TB90 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9407879 0.88 CA12 (0.38) CA12CA1CA2CA7CA9
SCHEMBL8980310 0.79 ECE1 (0.41) CA12CA1CA2CA7CA9
SCHEMBL8980325 0.76 DPP4 (0.44) KDM4EL3MBTL1RAB9ATDP1NPC1
SCHEMBL31726107 0.75 CA12 (0.47) CA12CA1CA2CA7CA9
SCHEMBL19435480 0.73 PTK6 (0.40) ECE1MALT1TDP1ALDH1A1MEN1
SCHEMBL2401753 0.73 KDM4E (0.44) KDM4EL3MBTL1MALT1RAB9ATDP1
SCHEMBL2400631 0.73 MEN1 (0.54) KDM4EL3MBTL1TDP1ALDH1A1MEN1
SCHEMBL8996451 0.73 CA12 (0.74) CA12CA1CA2CA7CA9
SCHEMBL8980352 0.72 KDM4E (0.45) KDM4EL3MBTL1RAB9ATDP1NPC1
SCHEMBL6982304 0.72 KDM4E (0.39) KDM4EL3MBTL1MALT1RAB9ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0591786-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-05-15 EP disclosed