SCHEMBL6982304

SCHEMBL6982304

Cc1c(OC(=O)O)ccc2scnc12

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.39
PKM P14618 1/20 0.39
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
HKDC1 Q2TB90 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
EGLN1 Q9GZT9 1/20 0.33
DAO P14920 1/20 0.32
MAPT P10636 1/20 0.31
MALT1 Q9UDY8 1/20 0.31
FFAR1 O14842 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6984764 0.85 KDM4E (0.36) KDM4EPKMNPC1RAB9ATDP1
SCHEMBL6982298 0.76 KDM4E (0.42) KDM4EPKMNPC1RAB9AHKDC1
SCHEMBL6986068 0.75 MAPT (0.43) NPC1RAB9AMAPT
SCHEMBL6984168 0.73 ALDH1A1 (0.44) KDM4ENPC1RAB9AL3MBTL1MAPT
SCHEMBL8980273 0.72 CA12 (0.47) KDM4EPKMNPC1RAB9AHKDC1
SCHEMBL8980196 0.72 KDM4E (0.35) KDM4EPKMNPC1RAB9AHKDC1
SCHEMBL7158040 0.72 CA12 (0.40) KDM4ENPC1RAB9AL3MBTL1MAPT
SCHEMBL5544035 0.71 ALDH1A1 (0.33) KDM4EPKMNPC1RAB9AHKDC1
SCHEMBL5544044 0.71 ALDH1A1 (0.33) KDM4EPKMNPC1RAB9AHKDC1
SCHEMBL6979296 0.71 MAPT (0.46) KDM4ENPC1RAB9ATDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1177194-B1 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS BASF AG (DE) 2003-09-17 EP disclosed
EP-1177194-A1 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS BASF AKTIENGESELLSCHAFT (DE) 2002-02-06 EP disclosed
WO-2000068228-A1 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS BASF AKTIENGESELLSCHAFT (DE) 2000-11-16 WO disclosed