SCHEMBL8980352

SCHEMBL8980352

O=C(O)c1c(-c2ccccc2)ccc2scnc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.45
KMT2A Q03164 8/20 0.40
MEN1 O00255 7/20 0.40
RAB9A P51151 5/20 0.40
NPC1 O15118 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
MAPT P10636 2/20 0.40
LMNA P02545 1/20 0.40
SLC12A2 P55011 1/20 0.40
SLC12A5 Q9H2X9 1/20 0.40
FOLH1 Q04609 1/20 0.38
TRPV1 Q8NER1 2/20 0.38
NLRP3 Q96P20 1/20 0.37
TDP1 Q9NUW8 3/20 0.37
HKDC1 Q2TB90 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ALDH1A1 P00352 2/20 0.37
PKM P14618 2/20 0.37
POLB P06746 1/20 0.37
BLM P54132 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28015032 0.76 ALDH1A1 (0.37) KDM4EKMT2ASMN1; SMN2LMNATRPV1
SCHEMBL8980325 0.76 DPP4 (0.44) KDM4ERAB9ANPC1TDP1HKDC1
SCHEMBL23521242 0.73 FOLH1 (0.53) KDM4EKMT2AMEN1FOLH1ALDH1A1
SCHEMBL926871 0.73 NAMPT (0.46) KDM4EALDH1A1HSD17B10NAMPT
SCHEMBL8980273 0.72 CA12 (0.47) KDM4EKMT2AMEN1RAB9ANPC1
SCHEMBL27877183 0.70 ALDH1A1 (0.42) KDM4EALDH1A1HSD17B10NAMPT
SCHEMBL12637453 0.70 NAMPT (0.47) KDM4EKMT2AMEN1RAB9ANPC1
SCHEMBL21879681 0.69 CDC25B (0.50) KMT2AMEN1RAB9ASMN1; SMN2MAPT
SCHEMBL8980214 0.69 ADORA2A (0.40) KDM4EKMT2AMEN1RAB9ANPC1
SCHEMBL262049 0.68 ALDH1A1 (0.44) KDM4ERAB9ANPC1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0591786-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-05-15 EP disclosed
EP-0591786-A2 Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1994-04-13 EP disclosed