SCHEMBL8980301

SCHEMBL8980301

O=C(O)CCc1cc2ncsc2cc1-c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 7/20 0.45
PTGER3 P43115 7/20 0.45
PTGER1 P34995 6/20 0.45
PTGER2 P43116 6/20 0.45
FFAR1 O14842 5/20 0.43
FFAR4 Q5NUL3 4/20 0.43
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
HKDC1 Q2TB90 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TRPV1 Q8NER1 2/20 0.40
LTB4R Q15722 3/20 0.40
PRKAG1 P54619 1/20 0.39
PRKAA2 P54646 1/20 0.39
PRKAB1 Q9Y478 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8980140 0.80 NPC1 (0.44) FFAR1FFAR4KDM4ENPC1RAB9A
SCHEMBL8980391 0.78 NPC1 (0.42) FFAR1FFAR4KDM4ENPC1RAB9A
SCHEMBL8980299 0.74 KDM4E (0.41) FFAR1KDM4ENPC1RAB9AHKDC1
SCHEMBL8980233 0.72 NPC1 (0.42) FFAR1FFAR4KDM4ENPC1RAB9A
SCHEMBL6928722 0.72 PTGER4 (0.55) PTGER4PTGER3PTGER1PTGER2FFAR1
SCHEMBL418265 0.72 KDM4E (0.55) FFAR1FFAR4KDM4ENPC1RAB9A
SCHEMBL8980215 0.72 P4HTM (0.47) FFAR1FFAR4KDM4ENPC1RAB9A
Benzo[D]Thiazole SCHEMBL3809615 0.70 ALDH1A1 (0.68) KDM4ENPC1RAB9AHKDC1TDP1
SCHEMBL8980189 0.70 NPC1 (0.40) FFAR1FFAR4KDM4ENPC1RAB9A
SCHEMBL8980144 0.70 PPARG (0.44) FFAR4KDM4ENPC1RAB9AHKDC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0591786-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-05-15 EP disclosed
EP-0591786-A2 Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1994-04-13 EP disclosed