SCHEMBL8980389

SCHEMBL8980389

CCc1cc2ncsc2cc1C(C)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
KDM4E B2RXH2 2/20 0.41
HKDC1 Q2TB90 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
FFAR1 O14842 2/20 0.36
NTRK1 P04629 1/20 0.34
NTRK2 Q16620 1/20 0.34
AKR1C3 P42330 1/20 0.34
AKR1C2 P52895 1/20 0.34
ESR1 P03372 2/20 0.34
IRAK4 Q9NWZ3 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8980181 0.84 NPC1 (0.40) NPC1RAB9AKDM4EHKDC1TDP1
SCHEMBL24447316 0.83 TAS1R3 (0.38) NPC1RAB9AKDM4EHKDC1TDP1
SCHEMBL8980138 0.79 NPC1 (0.43) NPC1RAB9AKDM4EHKDC1TDP1
SCHEMBL13311451 0.76 NPC1 (0.42) NPC1RAB9AKDM4EHKDC1TDP1
SCHEMBL8980299 0.74 KDM4E (0.41) NPC1RAB9AKDM4EHKDC1TDP1
SCHEMBL24868156 0.73 NPC1 (0.42) NPC1RAB9AKDM4EHKDC1TDP1
SCHEMBL8980391 0.72 NPC1 (0.42) NPC1RAB9AKDM4EHKDC1TDP1
SCHEMBL8980212 0.72 FFAR1 (0.49) NPC1RAB9AKDM4EHKDC1TDP1
SCHEMBL418266 0.72 NPC1 (0.55) NPC1RAB9AKDM4EHKDC1TDP1
SCHEMBL8980189 0.70 NPC1 (0.40) NPC1RAB9AKDM4EHKDC1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0591786-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-05-15 EP disclosed
EP-0591786-A2 Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1994-04-13 EP disclosed