Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961789 | 0.79 | ALDH1A1 (0.45) | NPC1RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL209949 | 0.78 | ALDH1A1 (0.53) | NPC1RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL30014749 | 0.78 | ALDH1A1 (0.53) | NPC1RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL8802888 | 0.76 | ALDH1A1 (0.56) | NPC1RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL7018429 | 0.75 | ALDH1A1 (0.50) | NPC1RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL29590055 | 0.75 | ALDH1A1 (0.50) | NPC1RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL7668928 | 0.75 | MAPT (0.50) | NPC1RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL6840865 | 0.75 | KDM4E (0.50) | NPC1RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL9488344 | 0.74 | HPGD (0.79) | NPC1RAB9AHPGDALDH1A1TRPM8 | |
| SCHEMBL21450331 | 0.73 | ALDH1A1 (0.45) | NPC1RAB9AHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571822-A | AMINO-2-PHENYL-4-QUINOLONE DERIVATIVES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-11-05 | — | — | US | disclosed |
| WO-1996010563-A1 | 2-ARYL-4-QUINOLONES AS ANTITUMOR COMPOUNDS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-04-11 | — | — | WO | disclosed |