Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.48 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18645554 | 0.87 | NAAA (0.57) | KDM4EALDH1A1CDK1CSNK2A1NAAA | |
| SCHEMBL8980662 | 0.87 | KDM4E (0.58) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL24454271 | 0.85 | CSNK2A1 (0.51) | KDM4EALDH1A1CDK1CSNK2A1NAAA | |
| SCHEMBL18646519 | 0.84 | NAAA (0.67) | KDM4EALDH1A1CDK1CSNK2A1NAAA | |
| SCHEMBL12855992 | 0.84 | CSNK2A1 (0.54) | KDM4EALDH1A1CDK1CSNK2A1NAAA | |
| Gentisic Acid Ethanolamide SCHEMBL1179368 | 0.83 | NAAA (0.65) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL13753913 | 0.83 | CSNK2A1 (0.56) | KDM4EMAPTCSNK2A1NAAAGRM5 | |
| Gentisic Acid Ethanolamide SCHEMBL29379843 | 0.83 | NAAA (0.65) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL18645728 | 0.83 | NAAA (0.74) | KDM4EALDH1A1CDK1NAAAHTT | |
| SCHEMBL14243219 | 0.82 | SMN1; SMN2 (0.50) | KDM4EALDH1A1MAPTCASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007065261-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITORS | AMERICAN DIAGNOSTICA INC. (US) | 2007-06-14 | — | — | WO | disclosed |
| EP-0711286-A1 | BENZOXAZINONES AND BENZOTHIAZINONES ENDOWED WITH THERAPEUTIC ACTIVITY | ITALFARMACO S.p.A. (IT) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004048-A1 | BENZOXAZINONES AND BENZOTHIAZINONES ENDOWED WITH THERAPEUTIC ACTIVITY | ITALFARMACO S.P.A. (IT) | 1995-02-09 | — | — | WO | disclosed |