Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | GLA | P06280 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3139976 | 0.83 | ALDH1A1 (0.71) | KMT2AALDH1A1LMNAMAPTGAA | |
| SCHEMBL9320340 | 0.82 | ALDH1A1 (0.56) | KMT2AALDH1A1LMNAMAPTGAA | |
| SCHEMBL4830373 | 0.82 | ALDH1A1 (0.63) | KMT2AALDH1A1LMNAMAPTGAA | |
| SCHEMBL11251929 | 0.81 | MAPT (0.70) | KMT2AALDH1A1LMNAMAPTGAA | |
| SCHEMBL9319047 | 0.80 | MAPT (0.70) | KMT2AALDH1A1LMNAMAPTGAA | |
| SCHEMBL3133306 | 0.80 | ALDH1A1 (0.60) | KMT2AALDH1A1LMNAMAPTGAA | |
| SCHEMBL8981903 | 0.79 | ALDH1A1 (0.54) | KMT2AALDH1A1LMNAMAPTGAA | |
| SCHEMBL9319012 | 0.78 | MAPT (0.61) | KMT2AALDH1A1LMNAMAPTGAA | |
| SCHEMBL29276483 | 0.78 | ALDH1A1 (0.61) | KMT2AALDH1A1LMNAMAPTGAA | |
| SCHEMBL9283208 | 0.78 | MAPT (0.69) | KMT2AALDH1A1LMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234176-B2 | Pyrazoline compounds | CIBA GEIGY AG (CH) | 1996-05-22 | — | — | EP | disclosed |
| US-5308545-A | Pyrazoline compounds | CIBA-GEIGY CORPORATION (US) | 1994-05-03 | — | — | US | disclosed |
| US-4816590-A | Pyrazoline compounds and method of whitening | CIBA-GEIGY CORPORATION (US) | 1989-03-28 | — | — | US | disclosed |
| EP-0234176-A1 | Pyrazoline compounds | CIBA-GEIGY AG (CH) | 1987-09-02 | — | — | EP | disclosed |