Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 4/20 | 0.36 |
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.36 |
| ▸ | PTGS2 known ✓ | P35354 | 3/20 | 0.36 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.36 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | GLA | P06280 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.60 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4830373 | 0.88 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EGLALMNA | |
| SCHEMBL3139976 | 0.87 | ALDH1A1 (0.71) | ALDH1A1MAPTKDM4EGLALMNA | |
| SCHEMBL11251929 | 0.84 | MAPT (0.70) | ALDH1A1MAPTKDM4EGLALMNA | |
| SCHEMBL9319047 | 0.84 | MAPT (0.70) | ALDH1A1MAPTKDM4EGLALMNA | |
| SCHEMBL11544710 | 0.82 | MAPT (0.67) | ALDH1A1MAPTKDM4EGLALMNA | |
| SCHEMBL9319012 | 0.82 | MAPT (0.61) | ALDH1A1MAPTKDM4EGLALMNA | |
| SCHEMBL11476192 | 0.81 | MAPT (0.60) | ALDH1A1MAPTKDM4EGLALMNA | |
| SCHEMBL9283208 | 0.81 | MAPT (0.69) | ALDH1A1MAPTKDM4EGLALMNA | |
| SCHEMBL3138995 | 0.80 | KDM4E (0.64) | ALDH1A1MAPTKDM4EGLALMNA | |
| SCHEMBL554460 | 0.80 | KDM4E (0.64) | ALDH1A1MAPTKDM4EGLALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101120046-B | Molded article exhibiting multi-color effects, associated lighting device and resin | ARKEMA FRANCE | 2011-02-23 | — | — | CN | claimed |
| US-20080214706-A1 | Moulded Object Exhibiting a Polychromatic Effect, Associated Light Device and Resin | ARKEMA FRANCE (FR) | 2008-09-04 | — | — | US | claimed |
| EP-1848763-B1 | MOULDED OBJECT EXHIBITING A POLYCHROMATIC EFFECT, ASSOCIATED LIGHT DEVICE AND RESIN | ARKEMA FRANCE (FR) | 2008-04-16 | — | — | EP | claimed |
| CN-101120046-A | Molded article exhibiting multi-color effects, associated lighting device and resin | ARKEMA FRANCE (FR) | 2008-02-06 | — | — | CN | claimed |
| US-12303582-B2 | Composition for the treatment of nail fungus | OYSTERSHELL NV (BE) | 2025-05-20 | — | — | US | disclosed |
| US-20210299022-A1 | COMPOSITION FOR THE TREATMENT OF NAIL FUNGUS | OYSTERSHELL NV (BE) | 2021-09-30 | — | — | US | disclosed |
| EP-3884933-A1 | COMPOSITION FOR THE TREATMENT OF NAIL FUNGUS | Oystershell NV (BE) | 2021-09-29 | — | — | EP | disclosed |
| US-20210155879-A1 | Cleaning Compositions | RECKITT BENCKISER VANISH B.V. (NL) | 2021-05-27 | — | — | US | disclosed |
| CN-101120046-B | Molded article exhibiting multi-color effects, associated lighting device and resin | ARKEMA FRANCE | 2011-02-23 | — | — | CN | disclosed |
| US-7641765-B2 | Applying slurry containing optical brighteners | BASF AKTIENGESELLSCHAFT (DE) | 2010-01-05 | — | — | US | disclosed |
| EP-1438197-B1 | METHOD FOR INCREASING THE WHITENESS OF PAPER BY MEANS OF CATIONIC POLYELECTROLYTES | BASF SE (DE) | 2008-10-15 | — | — | EP | disclosed |
| US-20080214706-A1 | Moulded Object Exhibiting a Polychromatic Effect, Associated Light Device and Resin | ARKEMA FRANCE (FR) | 2008-09-04 | — | — | US | disclosed |
| US-20040154764-A1 | Applying slurry containing optical brighteners | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-12 | — | — | US | disclosed |
| EP-1438197-A2 | METHOD FOR INCREASING THE WHITENESS OF PAPER BY MEANS OF CATIONIC POLYELECTROLYTES | BASF AKTIENGESELLSCHAFT (DE) | 2004-07-21 | — | — | EP | disclosed |
| EP-1419298-A1 | METHOD FOR PRODUCTION OF COATED PAPER WITH EXTREME WHITENESS | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003052205-A1 | METHOD FOR PRODUCING PAPER, PAPERBOARD AND CARDBOARD | BASF AKTIENGESELLSCHAFT (DE) | 2003-06-26 | — | — | WO | disclosed |
| WO-2003022924-A1 | POLYMER DISPERSIONS COMPRISING VINYLAMIDE COPOLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-20 | — | — | WO | disclosed |
| WO-2003021041-A2 | METHOD FOR INCREASING THE WHITENESS OF PAPER BY MEANS OF CATIONIC POLYELECTROLYTES | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-13 | — | — | WO | disclosed |
| WO-2003020808-A1 | REINFORCEMENT OF THE EFFECT OF OPTICAL BRIGHTENERS BY MEANS OF POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-13 | — | — | WO | disclosed |
| WO-2003016624-A1 | METHOD FOR PRODUCTION OF COATED PAPER WITH EXTREME WHITENESS | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12303582-B2 | Composition for the treatment of nail fungus | DPM1, PIK3C3, ETF1 | CA1 1300/4885CA2 595/4885PTGS2 4367/4885 |
| US-20210299022-A1 | COMPOSITION FOR THE TREATMENT OF NAIL FUNGUS | DPM1, PIK3C3, ETF1 | CA1 1300/4885CA2 595/4885PTGS2 4367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.