SCHEMBL8981973

SCHEMBL8981973

Cc1ccc(NC(=O)O)c(-c2cccc(C(F)(F)F)c2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.51
DHODH Q02127 1/20 0.51
GRIK1 P39086 1/20 0.50
SLC1A3 P43003 3/20 0.48
SLC1A2 P43004 3/20 0.48
SLC1A1 P43005 3/20 0.48
TOP2A P11388 1/20 0.48
MEN1 O00255 2/20 0.47
HTT P42858 2/20 0.47
KMT2A Q03164 2/20 0.47
RAB9A P51151 1/20 0.47
CHRM3 P20309 1/20 0.47
AKR1C3 P42330 1/20 0.46
AKR1C2 P52895 1/20 0.46
KCNK3 O14649 1/20 0.46
KCNK9 Q9NPC2 1/20 0.46
KIF11 P52732 1/20 0.46
TACR1 P25103 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
XDH P47989 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8981673 0.90 TACR1 (0.49) ALDH1A1DHODHGRIK1SLC1A3SLC1A2
SCHEMBL16438557 0.86 CHRM3 (0.54) ALDH1A1DHODHGRIK1SLC1A3SLC1A2
SCHEMBL8981764 0.85 CHRM3 (0.47) ALDH1A1DHODHGRIK1SLC1A3SLC1A2
SCHEMBL8981763 0.85 CHRM3 (0.47) ALDH1A1DHODHGRIK1SLC1A3SLC1A2
Trifluoroacetic Acid SCHEMBL5103795 0.85 CHRM3 (0.42) ALDH1A1MEN1KMT2ACHRM3AKR1C3
SCHEMBL5113247 0.85 ALDH1A1 (0.69) ALDH1A1GRIK1SLC1A3SLC1A2SLC1A1
SCHEMBL8981599 0.84 SLC1A3 (0.55) ALDH1A1DHODHGRIK1SLC1A3SLC1A2
SCHEMBL8981793 0.84 CHRM3 (0.44) ALDH1A1DHODHGRIK1SLC1A3SLC1A2
SCHEMBL8981696 0.82 LMNA (0.45) ALDH1A1DHODHGRIK1SLC1A3SLC1A2
SCHEMBL16438547 0.82 CHRM3 (0.56) TOP2ACHRM3KCNK3KCNK9SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0619804-B1 HERBICIDAL ACYLATED AMINO-(PHENYL- OR PYRIDINYL- OR THIENYL-)-PHENYL DERIVATIVES DU PONT (US) 1996-05-22 EP claimed