Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8981980 | 1.00 | DNMT3A (0.57) | DNMT3AHDAC1HDAC6NLRP3LMNA | |
| SCHEMBL8981982 | 1.00 | DNMT3A (0.57) | DNMT3AHDAC1HDAC6NLRP3LMNA | |
| SCHEMBL8981902 | 0.94 | DNMT3A (0.64) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL8981845 | 0.89 | LMNA (0.52) | DNMT3AHDAC1HDAC6NLRP3LMNA | |
| SCHEMBL8981831 | 0.89 | LMNA (0.52) | DNMT3AHDAC1HDAC6NLRP3LMNA | |
| SCHEMBL8981839 | 0.89 | LMNA (0.52) | DNMT3AHDAC1HDAC6NLRP3LMNA | |
| SCHEMBL8458179 | 0.88 | KMT2A (0.55) | DNMT3AHDAC1HDAC6NLRP3LMNA | |
| SCHEMBL8981741 | 0.86 | LMNA (0.49) | DNMT3AHDAC1HDAC6NLRP3LMNA | |
| SCHEMBL8981737 | 0.86 | LMNA (0.49) | DNMT3AHDAC1HDAC6NLRP3LMNA | |
| SCHEMBL8981731 | 0.86 | LMNA (0.49) | DNMT3AHDAC1HDAC6NLRP3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478853-A | Antidiabetic agents | ADIR ET COMPAGNIE (FR) | 1995-12-26 | — | — | US | claimed |
| US-5506245-A | TREATMENT OF INSULIN-RESISTANT AND/OR NON INSULIN-DEPENDENT DIABETES | ADIR ET COMPAGNIE (FR) | 1996-04-09 | — | — | US | disclosed |
| US-5478853-A | Antidiabetic agents | ADIR ET COMPAGNIE (FR) | 1995-12-26 | — | — | US | disclosed |