Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.67 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.67 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4700798 | 0.95 | ALDH1A1 (0.71) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL6025353 | 0.89 | ALDH1A1 (0.62) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL2991784 | 0.86 | CHRM2 (0.68) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL30775585 | 0.86 | CHRM2 (0.68) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL1102038 | 0.81 | CHRM2 (0.70) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL29930459 | 0.80 | CHRM2 (1.00) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL28643439 | 0.80 | CHRM2 (1.00) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL11881953 | 0.79 | ALDH1A1 (0.62) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL9974151 | 0.79 | CHRM2 (0.68) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL29930254 | 0.79 | CHRM2 (1.00) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711283-A1 | TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995003281-A1 | TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-02-02 | — | — | WO | disclosed |
| EP-0322779-A2 | Benzolactam compounds and pharmaceutical uses thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |