Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8834212 | 0.82 | NR4A2 (0.68) | KMT2ARAB9ANPC1NR4A2SMN1; SMN2 | |
| SCHEMBL16552727 | 0.73 | GSK3B (0.70) | KMT2ARAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL7701624 | 0.72 | KMT2A (0.35) | KMT2ARAB9ANPC1NR4A2SMN1; SMN2 | |
| SCHEMBL15094064 | 0.71 | NR4A2 (0.65) | KMT2ARAB9ANR4A2SMN1; SMN2HSD17B10 | |
| SCHEMBL4476891 | 0.71 | NR4A2 (0.65) | KMT2ARAB9ANPC1NR4A2SMN1; SMN2 | |
| SCHEMBL27983192 | 0.71 | NPC1 (0.81) | KMT2ARAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL271455 | 0.70 | MEN1 (0.52) | KMT2ARAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL28594420 | 0.70 | TSHR (0.67) | KMT2ARAB9ANPC1NR4A2SMN1; SMN2 | |
| SCHEMBL7939950 | 0.70 | NPC1 (0.81) | RAB9ANPC1LMNAALDH1A1GAA | |
| SCHEMBL10353454 | 0.70 | NR4A2 (0.81) | KMT2ARAB9ANPC1NR4A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712506-A1 | MUTABLE COMPOSITION AND METHODS OF USE THEREOF | KIMBERLY-CLARK CORPORATION (US) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995004955-A1 | MUTABLE COMPOSITION AND METHODS OF USE THEREOF | KIMBERLY-CLARK CORPORATION (US) | 1995-02-16 | — | — | WO | disclosed |