Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ERCC5 | P28715 | 3/20 | 0.50 |
| ▸ | FEN1 | P39748 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GSK3B | P49841 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29113253 | 0.91 | ERCC5 (0.64) | MEN1KMT2AMAPTKDM4EALOX15 | |
| SCHEMBL28991602 | 0.89 | PLOD2 (0.60) | MEN1KMT2AMAPK1MAPTCYP3A4 | |
| SCHEMBL9291396 | 0.87 | KMT2A (0.73) | MEN1KMT2AMAPK1MAPTCYP3A4 | |
| SCHEMBL8359255 | 0.83 | ALDH1A1 (0.62) | KMT2AMAPK1MAPTALOX15CES1 | |
| SCHEMBL7367689 | 0.77 | KMT2A (0.73) | MEN1KMT2AMAPK1MAPTCYP3A4 | |
| SCHEMBL7449918 | 0.77 | PTPN1 (0.62) | MEN1KMT2AMAPK1MAPTCYP3A4 | |
| SCHEMBL600674 | 0.76 | ERCC5 (0.72) | MEN1KMT2AMAPK1MAPTCYP3A4 | |
| SCHEMBL14660404 | 0.74 | MAPT (0.60) | MEN1KMT2AMAPK1MAPTCYP3A4 | |
| SCHEMBL29249309 | 0.74 | KMT2A (0.62) | MEN1KMT2AMAPK1MAPTCYP3A4 | |
| SCHEMBL6611633 | 0.73 | PLOD2 (0.71) | MEN1KMT2ACYP3A4HPGDPLOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133997-B2 | 2,4-dioxopyrimidine-based mesoionic pigments | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2012-03-13 | — | — | US | disclosed |
| US-20070185325-A1 | 2,4-dioxopyrimidine-based mesoionic pigments | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2007-08-09 | — | — | US | disclosed |