Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 10/20 | 0.45 |
| ▸ | ACACA | Q13085 | 6/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283668 | 0.83 | ACACB (0.49) | ACACBACACADRD2CKS1BSKP1 | |
| SCHEMBL8757882 | 0.81 | ACACB (0.47) | SMN1; SMN2ACACBACACADRD2CKS1B | |
| SCHEMBL8728457 | 0.78 | ACACB (0.50) | ACACBACACA | |
| SCHEMBL8982158 | 0.78 | TBXA2R (0.57) | SMN1; SMN2 | |
| SCHEMBL8882262 | 0.78 | ACACB (0.48) | ACACBACACADRD2CKS1BSKP1 | |
| SCHEMBL8733581 | 0.78 | ACACB (0.47) | ACACBACACADRD2CKS1BSKP1 | |
| SCHEMBL8729260 | 0.77 | POLB (0.46) | SMN1; SMN2ACACB | |
| SCHEMBL22534289 | 0.77 | ACACB (0.47) | SMN1; SMN2ACACBACACADRD2NAMPT | |
| SCHEMBL8879555 | 0.76 | TBXA2R (0.46) | ACACBACACADRD2NAMPT | |
| SCHEMBL9688045 | 0.73 | ALOX15 (0.49) | ACACBACACADRD2CKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589037-B1 | INDIAN DERIVATIVE AND THROMBOXANE ANTAGONIST CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-05-29 | — | — | EP | disclosed |
| US-5409956-A | A sulfonylaminoalkylindan carboxylic acid or ester for treating thrombosis, vasospasm or asthma | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0589037-A1 | INDIAN DERIVATIVE AND THROMBOXANE ANTAGONIST CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-30 | — | — | EP | disclosed |