SCHEMBL8982693

SCHEMBL8982693

N#Cc1ccc(NC(=O)Nc2ccc(N)cc2O)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CXCR2 P25025 4/20 0.67
▸ CXCR1 P25024 3/20 0.67
▸ CA12 O43570 4/20 0.56
▸ CA1 P00915 4/20 0.56
▸ CA2 P00918 4/20 0.56
▸ CA9 Q16790 4/20 0.56
▸ MAPT P10636 4/20 0.54
▸ LMNA P02545 3/20 0.54
▸ TSHR P16473 1/20 0.54
▸ HTT P42858 1/20 0.54
▸ NLRP3 Q96P20 1/20 0.54
▸ MEN1 O00255 2/20 0.54
▸ KMT2A Q03164 2/20 0.54
▸ ALDH1A1 P00352 2/20 0.54
▸ RAB9A P51151 2/20 0.52
▸ SAE1 Q9UBE0 1/20 0.52
▸ UBA2 Q9UBT2 1/20 0.52
▸ KDM4E B2RXH2 1/20 0.52
▸ POLB P06746 1/20 0.52
▸ PKM P14618 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4359536 0.86 CXCR1 (0.70) CXCR2CXCR1CA12CA1CA2
SCHEMBL11896323 0.83 MAPT (0.70) CXCR2CXCR1CA12CA1CA2
SCHEMBL6565641 0.83 CXCR2 (0.68) CXCR2CXCR1CA12CA1CA2
SCHEMBL9267208 0.82 CXCR1 (0.70) CXCR2CXCR1CA12CA1CA2
SCHEMBL7549704 0.81 CXCR2 (0.68) CXCR2CXCR1CA12CA1CA2
SCHEMBL8982664 0.80 MAPT (0.57) CXCR2CXCR1CA12CA1CA2
SCHEMBL7489930 0.80 CXCR2 (1.00) CXCR2CXCR1CA12CA1CA2
SCHEMBL5595077 0.78 CXCR2 (0.85) CXCR2CXCR1CA12CA1CA2
SCHEMBL11054945 0.78 MAPT (0.81) CXCR2CXCR1CA12CA1CA2
SCHEMBL10957092 0.78 CXCR2 (0.60) CXCR2CXCR1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0430335-B1 Improved method of synthesizing phenolic cyan-dye-forming photographic couplers EASTMAN KODAK CO (US) 1995-12-27 — — EP claimed
US-5041605-A Contacting coupler intermediate having nitro group with hydrogen donor, acylating EASTMAN KODAK COMPANY (US) 1991-08-20 — — US claimed
EP-0430335-A2 Improved method of synthesizing phenolic cyan-dye-forming photographic couplers EASTMAN KODAK COMPANY (US) 1991-06-05 — — EP claimed
JP-3174536-A — — None — — JP disclosed
EP-0423764-B1 Silver halide colour photographic material and cyan coupler of the 2-phenylureido-5-acylaminophenol type FUJI PHOTO FILM CO LTD (JP) 1996-05-08 — — EP disclosed
EP-0430335-B1 Improved method of synthesizing phenolic cyan-dye-forming photographic couplers EASTMAN KODAK CO (US) 1995-12-27 — — EP disclosed
US-5192651-A Color photography FUJI PHOTO FILM CO. LTD. (JP) 1993-03-09 — — US disclosed
US-5094938-A High coupling reactivity, high color density FUJI PHOTO FILM CO., LTD. (JP) 1992-03-10 — — US disclosed
US-5041605-A Contacting coupler intermediate having nitro group with hydrogen donor, acylating EASTMAN KODAK COMPANY (US) 1991-08-20 — — US disclosed
US-5041605-A Contacting coupler intermediate having nitro group with hydrogen donor, acylating EASTMAN KODAK COMPANY (US) 1991-08-20 — — US disclosed
JP-H03174536-A IMPROVED METHOD FOR SYNTHESIZING PHENOL TYPE CYAN DYE FORMING PHOTOGRAPHIC COUPLER EASTMAN KODAK CO 1991-07-29 — — JP disclosed
EP-0434028-A2 Silver halide color photographic photosensitive materials Fuji Photo Film Co., Ltd. (JP) 1991-06-26 — — EP disclosed
EP-0430335-A2 Improved method of synthesizing phenolic cyan-dye-forming photographic couplers EASTMAN KODAK COMPANY (US) 1991-06-05 — — EP disclosed
EP-0430335-A2 Improved method of synthesizing phenolic cyan-dye-forming photographic couplers EASTMAN KODAK COMPANY (US) 1991-06-05 — — EP disclosed
EP-0423764-A2 Silver halide colour photographic material and cyan coupler of the 2-phenylureido-5-acylaminophenol type FUJI PHOTO FILM CO., LTD. (JP) 1991-04-24 — — EP disclosed
US-4513082-A HYDROXYARYLSULFONYL COPULERS FUJI PHOTO FILM CO., LTD. (JP) 1985-04-23 — — US disclosed
US-4495272-A CYAN COLOR IMAGE FORMING POLYMER COUPLER LATEX FUJI PHOTO FILM CO., LTD. (JP) 1985-01-22 — — US disclosed
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