Butyrolactone

Butyrolactone

SCHEMBL8984027

CCC1(CC)OC(=O)COC1=O.O=C1CCCO1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.42
CA9 Q16790 1/20 0.42
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34628 0.86 HSD11B1 (0.31)
Butyrolactone SCHEMBL9507414 0.72 CA1 (0.64) CA1CA9ALDH1A1LMNATP53
Butyrolactone SCHEMBL17193239 0.71 CA1 (0.47) CA1CA9ALDH1A1LMNATP53
Butyrolactone SCHEMBL10420051 0.70
Butyrolactone SCHEMBL1271043 0.70 CA1 (0.82) CA1CA9ALDH1A1LMNATP53
Butyrolactone SCHEMBL27720055 0.70 CA1 (0.82) CA1CA9ALDH1A1LMNATP53
SCHEMBL19638361 0.70 CA1 (0.82) CA1CA9ALDH1A1LMNATP53
Butyrolactone SCHEMBL9421121 0.70
Butyrolactone SCHEMBL29433925 0.70
Butyrolactone SCHEMBL13481 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714666-A1 Hard tissue bone cements and substitutes ETHICON, INC. (US) 1996-06-05 EP disclosed