Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | ACHE | P22303 | 10/20 | 0.58 |
| ▸ | BCHE | P06276 | 5/20 | 0.58 |
| ▸ | BACE1 | P56817 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RAD52 | P43351 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875822 | 0.92 | KMT2A (0.57) | KMT2AKDM4EMEN1HTTACHE | |
| SCHEMBL9875000 | 0.92 | KDM4E (0.57) | KMT2AKDM4EMEN1HTTACHE | |
| SCHEMBL9873820 | 0.92 | KDM4E (0.57) | KMT2AKDM4EMEN1HTTACHE | |
| SCHEMBL9876065 | 0.89 | KMT2A (0.55) | KMT2AKDM4EMEN1HTTACHE | |
| SCHEMBL9875441 | 0.89 | KDM4E (0.54) | KMT2AKDM4EMEN1HTTACHE | |
| SCHEMBL9875622 | 0.89 | KDM4E (0.54) | KMT2AKDM4EMEN1HTTACHE | |
| SCHEMBL9875649 | 0.89 | MEN1 (0.54) | KMT2AKDM4EMEN1HTTACHE | |
| SCHEMBL9875619 | 0.89 | KDM4E (0.54) | KMT2AKDM4EMEN1HTTACHE | |
| SCHEMBL9875287 | 0.89 | KMT2A (0.54) | KMT2AKDM4EMEN1HTTACHE | |
| SCHEMBL9686349 | 0.88 | KMT2A (0.53) | KMT2AKDM4EMEN1HTTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4631286-A | MEMORY ENHANCERS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1986-12-23 | — | — | US | claimed |
| EP-2681554-B1 | BLOOD COLLECTION DEVICE CONTAINING LYSOPHOSPHOLIPASE INHIBITOR | BECTON DICKINSON CO (US) | 2017-08-09 | — | — | EP | disclosed |
| US-9459187-B2 | Blood collection device containing lysophospholipase inhibitor | BECTON, DICKINSON AND COMPANY (US) | 2016-10-04 | — | — | US | disclosed |
| US-20140030754-A1 | BLOOD COLLECTION DEVICE CONTAINING LYSOPHOSPHOLIPASE INHIBITOR | BECTON, DICKINSON AND COMPANY (US) | 2014-01-30 | — | — | US | disclosed |
| US-20130209985-A1 | SAMPLE COLLECTION DEVICES WITH BLOOD STABILIZING AGENTS | BECTON, DICKINSON AND COMPANY | 2013-08-15 | — | — | US | disclosed |
| EP-0449172-B1 | A method of reducing a carbonyl containing acridine | HOECHST ROUSSEL PHARMA (US) | 1996-06-05 | — | — | EP | disclosed |
| EP-0449172-A1 | A method of reducing a carbonyl containing acridine | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-10-02 | — | — | EP | disclosed |
| US-5053513-A | Catalytic hydrogenation using noble metal catalyst, lithium hydroxide, solvent | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-10-01 | — | — | US | disclosed |
| EP-0179383-B1 | 9-AMINO-1,2,3,4-TETRAHYDROACRIDIN-1-OL AND RELATED COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-05-29 | — | — | EP | disclosed |
| US-4839364-A | ALZHEIMER*S DISEASE; CHOLINESTERASE INHIBITORS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-06-13 | — | — | US | disclosed |
| US-4835275-A | Method of preparing 9-amino-1,2,3,4,-tetrahydroacridin-1-ones and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-05-30 | — | — | US | disclosed |
| US-4754050-A | COGNITION ACTIVATORS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-06-28 | — | — | US | disclosed |
| US-4695573-A | COGNITION ACTIVATORS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1987-09-22 | — | — | US | disclosed |
| US-4631286-A | MEMORY ENHANCERS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1986-12-23 | — | — | US | disclosed |
| EP-0179383-A2 | 9-Amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1986-04-30 | — | — | EP | disclosed |