Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TKT | P29401 | 11/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18837645 | 0.98 | LMNA (0.56) | LMNAHTTTP53ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7617650 | 0.97 | LMNA (0.59) | LMNAHTTTP53ALDH1A1KDM4E | |
| Iodide SCHEMBL16036467 | 0.97 | LMNA (0.55) | LMNAHTTTP53ALDH1A1KDM4E | |
| Fluoride Ion SCHEMBL16038833 | 0.97 | LMNA (0.55) | LMNAHTTTP53ALDH1A1KDM4E | |
| Bromide SCHEMBL7625997 | 0.88 | TKT (0.60) | LMNAHTTTP53ALDH1A1MEN1 | |
| SCHEMBL2900332 | 0.86 | TKT (0.61) | LMNAHTTTP53ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL29995247 | 0.84 | TKT (0.60) | LMNAHTTTP53ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL21337 | 0.84 | LMNA (0.63) | LMNAHTTTP53ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL9574573 | 0.82 | LMNA (0.56) | LMNAHTTTP53ALDH1A1KDM4E | |
| Bromide SCHEMBL27707079 | 0.80 | ALDH1A1 (0.54) | LMNAHTTTP53ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968643-B1 | CLAY COMPOSITES AND THEIR APPLICATIONS | MAT MODIFICATION INC (US) | 2018-09-05 | — | — | EP | claimed |
| US-20180043049-A1 | MULTIFUNCTIONAL TRANSDERMAL DRESSING FOR WOUNDS | MATERIALS MODIFICATION INC. | 2018-02-15 | — | — | US | claimed |
| US-20140276484-A1 | Clay Composites and their Applications | MATERIALS MODIFICATION INC (US) | 2014-09-18 | — | — | US | claimed |
| US-10272172-B2 | Multifunctional transdermal dressing for wounds | MATERIALS MODIFICATION INC (US) | 2019-04-30 | — | — | US | disclosed |
| EP-2968643-B1 | CLAY COMPOSITES AND THEIR APPLICATIONS | MAT MODIFICATION INC (US) | 2018-09-05 | — | — | EP | disclosed |
| US-20180043049-A1 | MULTIFUNCTIONAL TRANSDERMAL DRESSING FOR WOUNDS | MATERIALS MODIFICATION INC. | 2018-02-15 | — | — | US | disclosed |
| US-20140276484-A1 | Clay Composites and their Applications | MATERIALS MODIFICATION INC (US) | 2014-09-18 | — | — | US | disclosed |
| EP-0476567-B1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1996-06-12 | — | — | EP | disclosed |
| US-5217645-A | Low temperature, high speed response | CANON KABUSHIKI KAISHA (JP) | 1993-06-08 | — | — | US | disclosed |
| EP-0476567-A1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1992-03-25 | — | — | EP | disclosed |