Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 5/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RARB | P10826 | 3/20 | 0.52 |
| ▸ | RARA | P10276 | 1/20 | 0.52 |
| ▸ | RARG | P13631 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455852 | 0.86 | RARB (0.68) | CYP3A4RARBRARARARGESR1 | |
| SCHEMBL25797815 | 0.86 | RARB (0.68) | CYP3A4RARBRARARARGESR1 | |
| SCHEMBL8024671 | 0.86 | RARB (0.68) | CYP3A4RARBRARARARGESR1 | |
| SCHEMBL9775756 | 0.84 | RARB (0.65) | CYP3A4RARBRARARARGESR1 | |
| SCHEMBL8883008 | 0.84 | RARB (0.47) | HSD17B1HSD17B2CYP3A4RARBRARA | |
| SCHEMBL9164837 | 0.83 | KDM4E (0.56) | CYP3A4RARBRARARARGESR1 | |
| SCHEMBL2466020 | 0.83 | HSD17B10 (0.55) | CYP3A4RARBRARAESR1ADRA2A | |
| SCHEMBL6418801 | 0.83 | HSD17B10 (0.55) | CYP3A4RARBRARAESR1ADRA2A | |
| SCHEMBL8984295 | 0.82 | RARB (0.47) | HSD17B2RARBRARARARGMGLL | |
| SCHEMBL8984270 | 0.82 | ESR1 (0.71) | CYP3A4RARBRARAESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476567-B1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1996-06-12 | — | — | EP | disclosed |
| US-5217645-A | Low temperature, high speed response | CANON KABUSHIKI KAISHA (JP) | 1993-06-08 | — | — | US | disclosed |
| EP-0476567-A1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1992-03-25 | — | — | EP | disclosed |