Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8984329 | 1.00 | ALOX5AP (0.46) | ALOX5APGPBAR1ADAMTS4CYP1A2CYSLTR1 | |
| SCHEMBL7298298 | 0.84 | ADAMTS4 (0.55) | GPBAR1ADAMTS4CYP1A2CYSLTR1CYSLTR2 | |
| SCHEMBL7307096 | 0.84 | ADAMTS4 (0.55) | GPBAR1ADAMTS4CYP1A2CYSLTR1CYSLTR2 | |
| SCHEMBL7295767 | 0.82 | GPBAR1 (0.46) | GPBAR1ADAMTS4CYP1A2CYSLTR1CYSLTR2 | |
| SCHEMBL7306877 | 0.80 | CYP1A2 (0.48) | GPBAR1ADAMTS4CYP1A2CYSLTR1CYSLTR2 | |
| SCHEMBL7306884 | 0.80 | CYP1A2 (0.48) | GPBAR1ADAMTS4CYP1A2CYSLTR1CYSLTR2 | |
| SCHEMBL7304085 | 0.79 | CTSL (0.48) | GPBAR1ADAMTS4CYP1A2CYSLTR1CYSLTR2 | |
| SCHEMBL7299398 | 0.79 | CTSL (0.48) | GPBAR1ADAMTS4CYP1A2CYSLTR1CYSLTR2 | |
| SCHEMBL738204 | 0.78 | SYK (0.54) | — | |
| SCHEMBL478316 | 0.78 | SYK (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578608-A | HIV PROTEASE INHIBITOR | ELI LILLY AND COMPANY (US) | 1996-11-26 | — | — | US | disclosed |