Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17150269 | 0.90 | GPR3 (0.42) | GPR3PBRM1TNKS2HTR2AHTR2C | |
| SCHEMBL8984564 | 0.84 | CA12 (0.36) | GPR3PBRM1TNKS2NPC1RAB9A | |
| SCHEMBL1667065 | 0.84 | HTR2A (0.41) | GPR3PBRM1TNKS2HTR2AHTR2C | |
| SCHEMBL29945705 | 0.83 | GPR3 (0.50) | GPR3PBRM1TNKS2HTR2AHTR2C | |
| SCHEMBL8416742 | 0.83 | GPR3 (0.50) | GPR3PBRM1TNKS2HTR2AHTR2C | |
| SCHEMBL29490167 | 0.83 | HTR2A (0.48) | GPR3HTR2AGAA | |
| SCHEMBL1304934 | 0.83 | HTR2A (0.48) | GPR3HTR2AGAA | |
| SCHEMBL11804054 | 0.82 | PBRM1 (0.41) | GPR3PBRM1TNKS2HTR2AHTR2C | |
| SCHEMBL9348456 | 0.81 | HTR2C (0.39) | GPR3PBRM1TNKS2HTR2AHTR2C | |
| SCHEMBL9395349 | 0.79 | ESR2 (0.47) | HTR2BGAAHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387725-A | Chlorinating compounds having acidic protons with a perchloro-alkane and aqueous base in the presence of a tetraalkyl-ammonium hydroxide phase transfer catalyst | THE DOW CHEMICAL COMPANY (US) | 1995-02-07 | — | — | US | claimed |
| US-5578737-A | SUBSTITUTED FLUORENES, MONOMERS FOR HIGH PERFORMANCE POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1996-11-26 | — | — | US | disclosed |
| US-5387725-A | Chlorinating compounds having acidic protons with a perchloro-alkane and aqueous base in the presence of a tetraalkyl-ammonium hydroxide phase transfer catalyst | THE DOW CHEMICAL COMPANY (US) | 1995-02-07 | — | — | US | disclosed |