Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416742 | 1.00 | GPR3 (0.50) | GPR3HTR2APBRM1TNKS2TSHR | |
| SCHEMBL17150269 | 0.85 | GPR3 (0.42) | GPR3HTR2APBRM1TNKS2TSHR | |
| SCHEMBL29875704 | 0.84 | HTR2C (0.44) | GPR3HTR2APBRM1TNKS2TSHR | |
| SCHEMBL8984572 | 0.83 | GPR3 (0.41) | GPR3HTR2APBRM1TNKS2TSHR | |
| Carbazole SCHEMBL28957628 | 0.83 | KIF11 (0.49) | GPR3PBRM1TNKS2ACHEGAA | |
| SCHEMBL1667065 | 0.81 | HTR2A (0.41) | GPR3HTR2APBRM1TNKS2TSHR | |
| SCHEMBL28351932 | 0.81 | KMT2A (0.49) | GPR3HTR2APBRM1TNKS2GAA | |
| SCHEMBL11807034 | 0.79 | KMT2A (0.53) | PBRM1TNKS2HTR2BGAACYP3A4 | |
| SCHEMBL11804054 | 0.79 | PBRM1 (0.41) | GPR3HTR2APBRM1TNKS2TSHR | |
| SCHEMBL8415215 | 0.79 | GPR3 (0.37) | GPR3HTR2APBRM1TNKS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884016-B | Arylamine derivatives and use thereof | 日产化学株式会社 | 2022-11-01 | — | — | CN | disclosed |