Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3867377 | 0.77 | TSHR (0.42) | CYP19A1KIF11MEN1KMT2ATSHR | |
| SCHEMBL238217 | 0.76 | KIF11 (0.41) | KIF11TSHRMAPK1 | |
| SCHEMBL9248895 | 0.74 | KIF11 (0.46) | KIF11MAPK1NPSR1LMNAHTT | |
| SCHEMBL14149500 | 0.69 | CYP19A1 (0.70) | MIFCYP19A1KIF11MEN1KMT2A | |
| SCHEMBL28729097 | 0.67 | TSHR (0.46) | MIFCYP19A1MEN1KMT2ATSHR | |
| SCHEMBL10398401 | 0.65 | KCNN4 (0.39) | CYP19A1KIF11MEN1KMT2ATSHR | |
| SCHEMBL9184761 | 0.65 | CYP19A1 (0.58) | MIFCYP19A1KIF11MEN1KMT2A | |
| SCHEMBL13865445 | 0.65 | KIF11 (0.66) | MIFCYP19A1KIF11MEN1KMT2A | |
| SCHEMBL11218539 | 0.65 | GRIN2D (0.56) | MIFCYP19A1MEN1KMT2ATSHR | |
| SCHEMBL8984623 | 0.64 | SLC6A4 (0.44) | MIFCYP19A1KIF11MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431409-B1 | A nonaqueous method for making silicone polymers | GEN ELECTRIC (US) | 1996-06-12 | — | — | EP | disclosed |
| EP-0431409-A2 | A nonaqueous method for making silicone polymers | GENERAL ELECTRIC COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |
| US-4950779-A | Nonaqueous method for making silicone oligomers | GENERAL ELECTRIC COMPANY (US) | 1990-08-21 | — | — | US | disclosed |