Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3867379 | 0.80 | TSHR (0.38) | IDO1AGXTKIF11CYP3A4CYP1A2 | |
| SCHEMBL238218 | 0.75 | CYP1A2 (0.48) | SLC6A2KIF11CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL9184761 | 0.70 | CYP19A1 (0.58) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL5177590 | 0.70 | SLC6A4 (0.50) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL28729097 | 0.67 | TSHR (0.46) | IDO1CYP19A1CYP3A4MEN1KMT2A | |
| SCHEMBL3658885 | 0.66 | SLC6A4 (0.56) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL73498 | 0.64 | SLC6A4 (0.67) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL462327 | 0.64 | SLC6A4 (0.54) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL28848601 | 0.64 | SLC6A4 (0.67) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL332504 | 0.64 | SLC6A4 (0.54) | SLC6A4SLC6A2HTR2AHRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431409-B1 | A nonaqueous method for making silicone polymers | GEN ELECTRIC (US) | 1996-06-12 | — | — | EP | disclosed |
| EP-0431409-A2 | A nonaqueous method for making silicone polymers | GENERAL ELECTRIC COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |