Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.61 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.55 |
| ▸ | NGFR | P08138 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8984759 | 0.95 | FTO (0.59) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL5116172 | 0.82 | MEN1 (0.66) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL8984673 | 0.81 | FTO (0.56) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL4100436 | 0.79 | FTO (0.60) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL1901643 | 0.79 | FTO (0.72) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL5120849 | 0.78 | FTO (0.68) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL14560564 | 0.77 | FTO (0.73) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL3861437 | 0.77 | FTO (0.69) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL7703786 | 0.77 | MEN1 (0.67) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL12237994 | 0.77 | FTO (0.69) | FTOPABPC1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618901-B1 | HIGHLY WATER SOLUBLE BIS-NAPHTHALIMIDES USEFUL AS ANTICANCER AGENTS | DU PONT MERCK PHARMA (US) | 1996-06-12 | — | — | EP | claimed |
| US-5488110-A | Highly water soluble bis-naphthalimides useful as anticancer agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-01-30 | — | — | US | claimed |
| EP-0618901-B1 | HIGHLY WATER SOLUBLE BIS-NAPHTHALIMIDES USEFUL AS ANTICANCER AGENTS | DU PONT MERCK PHARMA (US) | 1996-06-12 | — | — | EP | disclosed |
| EP-0618901-B1 | HIGHLY WATER SOLUBLE BIS-NAPHTHALIMIDES USEFUL AS ANTICANCER AGENTS | DU PONT MERCK PHARMA (US) | 1996-06-12 | — | — | EP | disclosed |
| US-5488110-A | Highly water soluble bis-naphthalimides useful as anticancer agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-01-30 | — | — | US | disclosed |
| US-5488110-A | Highly water soluble bis-naphthalimides useful as anticancer agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-01-30 | — | — | US | disclosed |
| EP-0618901-A1 | HIGHLY WATER SOLUBLE BIS-NAPHTHALIMIDES USEFUL AS ANTICANCER AGENTS. | DU PONT MERCK PHARMA (US) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993012092-A1 | HIGHLY WATER SOLUBLE BIS-NAPHTHALIMIDES USEFUL AS ANTICANCER AGENTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-06-24 | — | — | WO | disclosed |