Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | CTSS | P25774 | 5/20 | 0.59 |
| ▸ | CTSK | P43235 | 3/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.59 |
| ▸ | CTSB | P07858 | 1/20 | 0.59 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.54 |
| ▸ | APP | P05067 | 3/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14861038 | 0.84 | NPC1 (0.50) | ATMALDH1A1 | |
| SCHEMBL29401299 | 0.83 | NPC1 (0.63) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL3676166 | 0.83 | NPC1 (0.63) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL12203694 | 0.83 | NPC1 (0.63) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL3676162 | 0.83 | NPC1 (0.63) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL9299789 | 0.83 | ATM (0.63) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL7939304 | 0.83 | ATM (0.63) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL5651916 | 0.83 | CTSS (0.64) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL5651920 | 0.83 | CTSS (0.64) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL3152909 | 0.83 | CACNA1B (0.51) | ATMCTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541286-A | Bradykinin antagonist pseudopeptide derivatives of olefinic aminoalkanoic acids | SCIOS NOVA INC. (US) | 1996-07-30 | — | — | US | disclosed |
| US-5444048-A | Antiinflammatory agents, analgesics | SCIOS NOVA, INC. (US) | 1995-08-22 | — | — | US | disclosed |