Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520662 | 0.90 | APAF1 (0.59) | APAF1KDM4EPOLBMAPTRECQL | |
| SCHEMBL28797485 | 0.81 | APAF1 (0.51) | APAF1KDM4EPOLBMAPTRECQL | |
| SCHEMBL30404131 | 0.79 | SLC7A5 (0.60) | KDM4EPOLBMAPTRECQLL3MBTL1 | |
| SCHEMBL19295494 | 0.79 | KDM4E (0.53) | APAF1KDM4EPOLBMAPTRECQL | |
| SCHEMBL1818794 | 0.79 | SLC7A5 (0.60) | KDM4EPOLBMAPTRECQLL3MBTL1 | |
| SCHEMBL19295493 | 0.79 | KDM4E (0.53) | APAF1KDM4EPOLBMAPTRECQL | |
| SCHEMBL7629121 | 0.79 | KDM4E (0.53) | APAF1KDM4EPOLBMAPTRECQL | |
| SCHEMBL5311363 | 0.79 | POLB (0.57) | APAF1KDM4EPOLBMAPTRECQL | |
| SCHEMBL20513564 | 0.79 | SLC7A5 (0.60) | KDM4EPOLBMAPTRECQLL3MBTL1 | |
| SCHEMBL1818793 | 0.79 | SLC7A5 (0.60) | KDM4EPOLBMAPTRECQLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541286-A | Bradykinin antagonist pseudopeptide derivatives of olefinic aminoalkanoic acids | SCIOS NOVA INC. (US) | 1996-07-30 | — | — | US | disclosed |
| US-5444048-A | Antiinflammatory agents, analgesics | SCIOS NOVA, INC. (US) | 1995-08-22 | — | — | US | disclosed |