Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | APAF1 | O14727 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19295493 | 1.00 | KDM4E (0.53) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL19295494 | 1.00 | KDM4E (0.53) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL8520662 | 0.88 | APAF1 (0.59) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL24899379 | 0.85 | L3MBTL1 (0.46) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL430339 | 0.85 | L3MBTL1 (0.46) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL9817764 | 0.85 | PPARG (0.44) | KDM4EPPARGPPARAHPGDALDH1A1 | |
| SCHEMBL27851029 | 0.85 | PPARG (0.44) | KDM4EPPARGPPARAHPGDALDH1A1 | |
| SCHEMBL31112170 | 0.85 | PPARG (0.44) | KDM4EPPARGPPARAHPGDALDH1A1 | |
| SCHEMBL7437418 | 0.84 | KMT2A (0.58) | KDM4EL3MBTL1PPARGPPARAHPGD | |
| SCHEMBL31561609 | 0.84 | ALDH1A1 (0.50) | KDM4EL3MBTL1PPARGPPARAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109081827-A | A kind of preparation method and application of bilastine | 北京天弘天达医药科技股份有限公司 | 2018-12-25 | — | — | CN | disclosed |
| CN-104402773-A | Process for the preparation of 2-methyl-2' -phenylpropionic acid derivatives and intermediate compounds | YUHAN CORP | 2015-03-11 | — | — | CN | disclosed |
| CN-101952273-B | Process for the preparation of 2-methyl-2' -phenylpropionic acid derivatives and intermediate compounds | YUHAN CORP | 2014-11-12 | — | — | CN | disclosed |
| CN-101952273-A | Process for the preparation of 2-methyl-2' -phenylpropionic acid derivatives and novel intermediate compounds | YUHAN CORP | 2011-01-19 | — | — | CN | disclosed |
| EP-2251338-A2 | Organic compounds | Boehringer Ingelheim International GmbH (DE) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009065919-A2 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-28 | — | — | WO | disclosed |
| EP-1448523-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | NOVARTIS AG (CH) | 2007-08-22 | — | — | EP | disclosed |
| EP-0773204-B1 | Process for the preparation of an indene and use thereof for the preparation of metallocenes | BASELL POLYOLEFINE GMBH (DE) | 2002-12-04 | — | — | EP | disclosed |
| US-5843941-A | Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1998-12-01 | — | — | US | disclosed |
| EP-0773204-A2 | Process for the preparation of an indene and use thereof for the preparation of metallocenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-14 | — | — | EP | disclosed |
| EP-0763537-A2 | Non-peptidyl Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5532359-A | FUNGICIDES | GENENTECH, INC. (US) | 1996-07-02 | — | — | US | disclosed |
| EP-0698015-A1 | PREPARATION OF N-CYANODITHIOIMINO-CARBONATES AND 3-MERCAPTO-5-AMINO-1H-1,2,4-TRIAZOLE | GENENTECH, INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994026723-A2 | ras FARNESYL TRANSFERASE INHIBITORS | GENENTECH, INC. (US) | 1994-11-24 | — | — | WO | disclosed |
| US-5329033-A | Metallocene catalyst, indene containing ligands, alumoxane cocatalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |
| US-5278264-A | Catalytic polymerizing in presence of a transition metal metallocene | HOECHST AG (DE) | 1994-01-11 | — | — | US | disclosed |
| EP-0530647-A1 | Metallocenes, catalysts containing these and process for the manufacture of olefinic polymers by using these catalysts | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-10 | — | — | EP | disclosed |
| EP-0287084-B1 | ALCOHOLS CONTAINING 2-METHYL OR 2-METHOXYPHENYL GROUPS, AND THEIR USE AS FLAVOURING AGENTS | Consortium für elektrochemische Industrie GmbH (DE) | 1991-10-02 | — | — | EP | disclosed |
| US-4849401-A | Alcohols containing 2-methylphenyl or 2-methoxyphenyl groups, and fragrances containing same | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE, GMBH (DE) | 1989-07-18 | — | — | US | disclosed |
| EP-0287084-A2 | Alcohols containing 2-methyl or 2-methoxyphenyl groups, and their use as flavouring agents | Consortium für elektrochemische Industrie GmbH (DE) | 1988-10-19 | — | — | EP | disclosed |