Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27754655 | 0.82 | ALDH1A1 (0.46) | POLBGAAALDH1A1LMNAMAPT | |
| SCHEMBL11362056 | 0.77 | ALDH1A1 (0.38) | POLBGAAALDH1A1KDM4ELMNA | |
| SCHEMBL31267559 | 0.76 | ALDH1A1 (0.40) | POLBALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL2573857 | 0.75 | ALDH1A1 (0.40) | POLBGAAALDH1A1KDM4ELMNA | |
| SCHEMBL10928273 | 0.73 | ALDH1A1 (0.38) | POLBGAAALDH1A1KDM4ELMNA | |
| SCHEMBL7161466 | 0.72 | HRH3 (0.41) | GAAALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL4975096 | 0.71 | NCF1 (0.33) | ALDH1A1LMNAMAPTHPGDRAB9A | |
| SCHEMBL12186714 | 0.70 | ALDH1A1 (0.36) | POLBGAAALDH1A1KDM4ELMNA | |
| SCHEMBL4955705 | 0.70 | HRH3 (0.41) | GAAALDH1A1KDM4ELMNAUSP2 | |
| SCHEMBL10603631 | 0.68 | POLB (0.44) | POLBGAAALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716084-A1 | Preparation of 4,4'-(oxydi-2,1-ethanediyl)bis-morpholine and hydroxyethoxyethyl morpholine | HUNTSMAN CORPORATION (US) | 1996-06-12 | — | — | EP | disclosed |