Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | POLB | P06746 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31516298 | 1.00 | KMT2A (0.66) | KMT2APOLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8985172 | 0.87 | KMT2A (0.49) | KMT2APOLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3391734 | 0.84 | GRIN1 (0.55) | KMT2APOLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL31516312 | 0.81 | IDO1 (0.60) | KMT2APOLBKDM4EMAPTPIN1 | |
| SCHEMBL31516296 | 0.81 | TDP1 (0.64) | KMT2ARAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11339381 | 0.81 | TDP1 (0.64) | KMT2ARAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL10833217 | 0.80 | GRIN1 (0.55) | KMT2APOLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29732973 | 0.80 | GRIN1 (0.55) | KMT2APOLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6311638 | 0.80 | KMT2A (0.62) | KMT2APOLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10142439 | 0.80 | KMT2A (0.74) | KMT2APOLBRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110872288-A | Method for synthesizing benzimidazole [1,2-a ] quinoline compound | 浙江工业大学 | 2020-03-10 | — | — | CN | disclosed |
| US-5510494-A | REACTING AN ORTHO-PHENYLENEDIAMINE WITH A CYANOACETIC ESTER IN A HALOGEN-FREE INERT SOLVENT WITHOUT ADDING AN AROMATIC SULFONIC ACID AS CATALYST | HOECHST AG (DE) | 1996-04-23 | — | — | US | disclosed |
| US-4268668-A | FOR WOOL AND POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |
| US-4051099-A | ISOINDOLES | CIBA-GEIGY CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |