Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.54 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.52 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 8/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 6/20 | 0.50 |
| ▸ | CSNK1G2 | P78368 | 6/20 | 0.50 |
| ▸ | GSK3B | P49841 | 5/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391736 | 0.87 | GRIN1 (0.43) | GRIN1GRIN2BPIN1PKN1PKN2 | |
| SCHEMBL31516298 | 0.84 | KMT2A (0.66) | PIN1KMT2APOLBKDM4EMEN1 | |
| SCHEMBL8985181 | 0.84 | KMT2A (0.66) | PIN1KMT2APOLBKDM4EMEN1 | |
| SCHEMBL7653726 | 0.84 | TDP1 (0.59) | GRIN1GRIN2BPIN1PKN1PKN2 | |
| SCHEMBL7381841 | 0.84 | GRIN1 (0.55) | GRIN1GRIN2BPIN1PKN1PKN2 | |
| SCHEMBL22553665 | 0.81 | GRIN1 (0.53) | GRIN1GRIN2BPIN1PKN1PKN2 | |
| SCHEMBL7655135 | 0.81 | RAD52 (0.61) | GRIN1GRIN2BPIN1PKN1PKN2 | |
| SCHEMBL31516296 | 0.81 | TDP1 (0.64) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL31516312 | 0.81 | IDO1 (0.60) | PIN1METAP2METAP1KMT2APOLB | |
| SCHEMBL11339381 | 0.81 | TDP1 (0.64) | KMT2AKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954764-B1 | BENZOPYRAN COLORANTS, METHOD OF MANUFACTURE, AND METHOD OF USE | SABIC INNOVATIVE PLASTICS IP (NL) | 2010-12-22 | — | — | EP | disclosed |
| EP-1954764-A2 | BENZOPYRAN COLORANTS, METHOD OF MANUFACTURE, AND METHOD OF USE | General Electric Company (US) | 2008-08-13 | — | — | EP | disclosed |
| US-7351461-B2 | Articles comprising benzopyran colorants, method of manufacture, and method of use | GENERAL ELECTRIC COMPANY (US) | 2008-04-01 | — | — | US | disclosed |
| US-20070238817-A1 | Articles Comprising Benzopyran Colorants, Method Of Manufacture, And Method Of Use | GENERAL ELECTRIC COMPANY (US) | 2007-10-11 | — | — | US | disclosed |
| US-7270772-B2 | Benzopyran colorants, method of manufacture, and method of use | GENERAL ELECTRIC COMPANY (US) | 2007-09-18 | — | — | US | disclosed |
| WO-2007064563-A2 | BENZOPYRAN COLORANTS, METHOD OF MANUFACTURE, AND METHOD OF USE | GENERAL ELECTRIC COMPANY (US) | 2007-06-07 | — | — | WO | disclosed |
| US-20070122746-A1 | BENZOPYRAN COLORANTS, METHOD OF MANUFACTURE, AND METHOD OF USE | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2007-05-31 | — | — | US | disclosed |
| US-4097484-A | ORGANIC PIGMENTS, PLASTICS | CIBA-GEIGY CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |
| US-4002635-A | FOR COLORING PLASTICS AND LACQUERS | CIBA-GEIGY CORPORATION (US) | 1977-01-11 | — | — | US | disclosed |
| US-3994899-A | METHINE | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070122746-A1 | BENZOPYRAN COLORANTS, METHOD OF MANUFACTURE, AND METHOD OF USE | CBR3, CBR1, NQO1 | GRIN1 3915/4885GRIN2B 4371/4885PIN1 1481/4885 |
| US-20070238817-A1 | Articles Comprising Benzopyran Colorants, Method Of Manufacture, And Method Of Use | CBR3, CBR1, HCCS | GRIN1 4427/4885GRIN2B 4748/4885PIN1 875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.