Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LGMN | Q99538 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24493549 | 0.85 | KDM4E (0.47) | KMT2APOLBMAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL16340766 | 0.83 | KDM4E (0.46) | KMT2APOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL16067955 | 0.78 | POLB (0.46) | CYP2C19KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL31133127 | 0.78 | KMT2A (0.49) | CYP2C19GAAKMT2APOLBMAPT | |
| SCHEMBL30915761 | 0.78 | KDM4E (0.46) | CYP2C19KDM4EHPGDNPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL16056681 | 0.77 | POLB (0.45) | CYP2C19KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL8985213 | 0.76 | KMT2A (0.46) | CYP2C19KMT2APOLBMAPTKDM4E | |
| SCHEMBL408908 | 0.74 | KMT2A (0.46) | GAAKMT2APOLBMAPTKDM4E | |
| SCHEMBL24493337 | 0.74 | ALDH1A1 (0.45) | KMT2APOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL439468 | 0.72 | PKM (0.48) | KMT2AMAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547961-A | USING TETRAHYDROIMIDAZOPYRIDINE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| US-5336679-A | Treatment of irritable bowel syndrome | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1994-08-09 | — | — | US | disclosed |
| EP-0532754-A1 | TETRAHYDROIMIDAZOPYRIDINE DERIVATIVE OR ITS SALT | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-24 | — | — | EP | disclosed |