Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | EP300 | Q09472 | 7/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985311 | 0.87 | PTGS1 (0.51) | PTGS1EP300PTGS2MAPK14GCGR | |
| SCHEMBL8985550 | 0.82 | PTGS1 (0.54) | PTGS1EP300PTGS2MAPK14GCGR | |
| SCHEMBL8985330 | 0.80 | PTGS1 (0.49) | PTGS1PTGS2MAPK14GCGR | |
| Hydrochloric Acid SCHEMBL8985507 | 0.80 | PTGS2 (0.65) | PTGS1PTGS2 | |
| SCHEMBL8985538 | 0.80 | PTGS1 (0.51) | PTGS1EP300PTGS2MAPK14GCGR | |
| SCHEMBL8985346 | 0.79 | PTGS1 (0.48) | PTGS1EP300PTGS2MAPK14GCGR | |
| Hydrochloric Acid SCHEMBL8985440 | 0.79 | PTGS1 (0.50) | PTGS1EP300PTGS2MAPK14GCGR | |
| SCHEMBL8985175 | 0.77 | PTGS1 (0.46) | PTGS1EP300PTGS2MAPK14GCGR | |
| SCHEMBL8985278 | 0.76 | PTGS1 (0.47) | PTGS1EP300PTGS2MAPK14 | |
| SCHEMBL6050634 | 0.74 | PTGS2 (0.62) | PTGS1PTGS2MAPK14GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |