Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985175 | 0.91 | PTGS1 (0.46) | PTGS1PTGS2MAPK14EP300GCGR | |
| SCHEMBL8985330 | 0.89 | PTGS1 (0.49) | PTGS1PTGS2MAPK14GCGRKDM4E | |
| SCHEMBL8985538 | 0.89 | PTGS1 (0.51) | PTGS1PTGS2MAPK14EP300GCGR | |
| Hydrochloric Acid SCHEMBL8985440 | 0.88 | PTGS1 (0.50) | PTGS1PTGS2MAPK14EP300GCGR | |
| SCHEMBL8985341 | 0.82 | EP300 (0.41) | PTGS1PTGS2MAPK14EP300SLC6A2 | |
| SCHEMBL8985550 | 0.81 | PTGS1 (0.54) | PTGS1PTGS2MAPK14EP300GCGR | |
| Hydrochloric Acid SCHEMBL8985487 | 0.80 | PTGS2 (0.64) | PTGS1PTGS2KDM4EMT-CO1MT-CO2 | |
| SCHEMBL8985433 | 0.79 | PTGS2 (0.42) | PTGS1PTGS2MAPK14EP300KDM4E | |
| SCHEMBL8985246 | 0.79 | PTGS1 (0.49) | PTGS1PTGS2MAPK14EP300GCGR | |
| SCHEMBL8985223 | 0.79 | PTGS2 (0.50) | PTGS1PTGS2MAPK14EP300KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |