Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.63 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1181119 | 0.91 | PTGS2 (0.73) | PTGS2PTGS1MAPK14 | |
| Ammonia Solution, Strong SCHEMBL23908221 | 0.90 | PTGS2 (0.71) | PTGS2PTGS1MAPK14 | |
| SCHEMBL10843937 | 0.86 | MAPK14 (0.79) | PTGS2PTGS1MAPK14 | |
| SCHEMBL7167117 | 0.83 | PTGS2 (0.64) | PTGS2PTGS1MAPK14 | |
| SCHEMBL28254055 | 0.83 | PTGS2 (0.64) | PTGS2PTGS1MAPK14RAB9A | |
| SCHEMBL6517923 | 0.81 | PTGS1 (0.68) | PTGS2PTGS1MAPK14 | |
| SCHEMBL6513427 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL1181221 | 0.78 | PTGS2 (0.57) | PTGS2 | |
| SCHEMBL8985431 | 0.77 | PTGS1 (1.00) | PTGS2PTGS1MAPK14 | |
| SCHEMBL10567384 | 0.77 | PTGS1 (1.00) | PTGS2PTGS1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |