Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 11/20 | 1.00 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985431 | 1.00 | PTGS1 (1.00) | PTGS1MAPK14PTGS2 | |
| SCHEMBL10843937 | 0.86 | MAPK14 (0.79) | PTGS1MAPK14PTGS2 | |
| SCHEMBL8985534 | 0.83 | PTGS1 (0.71) | PTGS1MAPK14PTGS2 | |
| SCHEMBL8985256 | 0.83 | PTGS1 (0.70) | PTGS1MAPK14PTGS2 | |
| SCHEMBL8985536 | 0.83 | PTGS1 (0.70) | PTGS1MAPK14PTGS2 | |
| SCHEMBL6517923 | 0.81 | PTGS1 (0.68) | PTGS1MAPK14PTGS2 | |
| SCHEMBL8985476 | 0.77 | PTGS1 (0.62) | PTGS1PTGS2 | |
| SCHEMBL8985254 | 0.77 | PTGS2 (0.64) | PTGS1MAPK14PTGS2 | |
| SCHEMBL5254380 | 0.76 | MAPK14 (1.00) | PTGS1MAPK14PTGS2 | |
| SCHEMBL6050625 | 0.75 | PTGS2 (0.60) | PTGS1MAPK14PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4820827-A | 2,3-diaryl-5-bromothiophene compounds of use for the treatment of inflammaton and dysmenorrhea | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-04-11 | — | — | US | disclosed |