⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL85627 | 1.00 | — | — | |
| SCHEMBL7118718 | 1.00 | — | — | |
| Trimethylammonium SCHEMBL5786947 | 0.94 | CA2 (0.43) | — | |
| SCHEMBL4475938 | 0.84 | CA2 (0.46) | — | |
| SCHEMBL1526302 | 0.84 | CA2 (0.46) | — | |
| SCHEMBL1526299 | 0.84 | CA2 (0.46) | — | |
| SCHEMBL4421192 | 0.81 | — | — | |
| SCHEMBL589285 | 0.81 | — | — | |
| SCHEMBL589481 | 0.81 | — | — | |
| SCHEMBL740693 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024217515-A1 | HETEROCYCLIC RING-SUBSTITUTED AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海复宏汉霖生物技术股份有限公司 | 2024-10-24 | — | — | WO | disclosed |
| US-20230142119-A1 | TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-05-11 | — | — | US | disclosed |
| CN-111484543-B | Lipopeptide TLR2 agonist and medicinal composition and application thereof | 复旦大学 | 2023-03-28 | — | — | CN | disclosed |
| US-20220306578-A1 | TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-09-29 | — | — | US | disclosed |
| CN-111484543-A | Lipopeptide T L R2 agonist and medicinal composition and application thereof | 复旦大学 | 2020-08-04 | — | — | CN | disclosed |
| CN-109384773-B | Synthesis method of S-glycidol phthalimide | 新发药业有限公司 | 2020-07-17 | — | — | CN | disclosed |
| EP-3613729-A1 | TETRACYCLIC COMPOUNDS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-02-26 | — | — | EP | disclosed |
| EP-3345903-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2019-10-09 | — | — | EP | disclosed |
| CN-109384773-A | A kind of synthetic method of inexpensive, high-purity S- glycidol phthalimide | 新发药业有限公司 | 2019-02-26 | — | — | CN | disclosed |
| EP-3345903-A1 | TETRACYCLIC COMPOUNDS | Chugai Seiyaku Kabushiki Kaisha (JP) | 2018-07-11 | — | — | EP | disclosed |
| US-20160340308-A1 | TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-11-24 | — | — | US | disclosed |
| US-9440922-B2 | Tetracyclic compound | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-09-13 | — | — | US | disclosed |
| EP-2441753-B1 | TETRACYCLIC COMPOUND | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2016-03-30 | — | — | EP | disclosed |
| EP-2975024-A1 | TETRACYCLIC COMPOUNDS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-01-20 | — | — | EP | disclosed |
| US-9126931-B2 | Tetracyclic compound | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2015-09-08 | — | — | US | disclosed |
| US-20150150845-A1 | TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2015-06-04 | — | — | US | disclosed |
| WO-2015018333-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | FUJIAN HAIXI PHARMACEUTICALS CO., LTD (CN) | 2015-02-12 | — | — | WO | disclosed |
| WO-2015018333-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | FUJIAN HAIXI PHARMACEUTICALS CO., LTD (CN) | 2015-02-12 | — | — | WO | disclosed |
| EP-2441753-A1 | TETRACYCLIC COMPOUND | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-04-18 | — | — | EP | disclosed |
| US-20120083488-A1 | TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA | 2012-04-05 | — | — | US | disclosed |