Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.49 |
| ▸ | PLK4 | O00444 | 1/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | FES | P07332 | 1/20 | 0.49 |
| ▸ | ROS1 | P08922 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | FER | P16591 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985520 | 0.88 | MAPK14 (0.66) | MAPK14PTGS2PTGS1GCGRHSPB1 | |
| SCHEMBL8985339 | 0.87 | MAPK14 (0.67) | MAPK14PTGS2PTGS1MAPK1TSHR | |
| SCHEMBL8985451 | 0.84 | MAPK14 (0.50) | MAPK14PTGS2PTGS1TSHRGCGR | |
| SCHEMBL8985447 | 0.84 | MAPK14 (0.50) | MAPK14PTGS2PTGS1PLK1TSHR | |
| SCHEMBL8985292 | 0.82 | MAPK14 (0.57) | MAPK14PTGS2PTGS1CDC7PLK4 | |
| SCHEMBL8985461 | 0.80 | PTGS2 (0.68) | MAPK14PTGS2PTGS1CHEK2CDK1 | |
| SCHEMBL8985284 | 0.79 | PTGS2 (0.63) | MAPK14PTGS2PTGS1TSHRGCGR | |
| SCHEMBL8985420 | 0.76 | PTGS2 (0.50) | MAPK14PTGS2PTGS1TSHRGCGR | |
| SCHEMBL8985342 | 0.74 | MAPK14 (0.83) | MAPK14PTGS2PTGS1TSHR | |
| SCHEMBL28203797 | 0.74 | KMT2A (0.51) | MAPK14CDC7TSHRGCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |