Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.48 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985189 | 0.84 | PTGS2 (0.49) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| SCHEMBL8097094 | 0.84 | PTGS2 (0.70) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| SCHEMBL8985413 | 0.82 | PTGS2 (0.71) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| SCHEMBL8985497 | 0.81 | APP (0.35) | PTGS2 | |
| SCHEMBL8985195 | 0.78 | PTGS2 (0.47) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| SCHEMBL16965230 | 0.73 | CA12 (0.57) | PTGS2PTGS1CYP3A4HPGDHSD17B10 | |
| SCHEMBL2017578 | 0.72 | CA12 (0.64) | PTGS2PTGS1CYP3A4HPGDHSD17B10 | |
| SCHEMBL8985295 | 0.71 | PTGS2 (0.67) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| Hydrochloric Acid SCHEMBL28024787 | 0.70 | CA12 (0.61) | PTGS2PTGS1CYP3A4HPGDHSD17B10 | |
| SCHEMBL8985337 | 0.69 | PTGS2 (0.52) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |