Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 5/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985372 | 0.84 | PTGS2 (0.34) | PGRNR3C1NR3C2ARPTGS2 | |
| SCHEMBL8985456 | 0.81 | PTGS2 (0.51) | PTGS2 | |
| SCHEMBL8985506 | 0.81 | APP (0.33) | APP | |
| SCHEMBL8985296 | 0.81 | PTGS1 (0.44) | APPPTGS2 | |
| SCHEMBL8985378 | 0.78 | PGR (0.33) | PGRNR3C1NR3C2ARPTGS2 | |
| SCHEMBL8985478 | 0.77 | MAPK14 (0.48) | APPPTGS2MAPK14 | |
| SCHEMBL15824911 | 0.71 | TSHR (0.42) | APP | |
| SCHEMBL8985319 | 0.66 | PTGS2 (0.34) | PTGS2 | |
| SCHEMBL8985328 | 0.66 | PTGS1 (0.43) | PTGS2 | |
| SCHEMBL8985521 | 0.65 | PTGS1 (0.30) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |