Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NOS1 | P29475 | 3/20 | 0.57 |
| ▸ | NOS3 | P29474 | 2/20 | 0.57 |
| ▸ | BCHE | P06276 | 7/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13814621 | 0.87 | BCHE (0.73) | MEN1KMT2AMAPK1NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL9454945 | 0.86 | BCHE (0.71) | MEN1KMT2AMAPK1NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL29873726 | 0.86 | BCHE (0.71) | MEN1KMT2AMAPK1NOS1NOS3 | |
| SCHEMBL6417799 | 0.85 | ALDH1A1 (0.65) | MEN1KMT2ASMN1; SMN2NOS1NOS3 | |
| SCHEMBL13462917 | 0.83 | MAOB (0.60) | MEN1KMT2AMAPK1HTTSMN1; SMN2 | |
| SCHEMBL13948890 | 0.81 | ALDH1A1 (0.55) | MEN1KMT2AHTTSMN1; SMN2KDM4E | |
| SCHEMBL21634323 | 0.80 | MEN1 (0.65) | MEN1KMT2AMAPK1HTTSMN1; SMN2 | |
| SCHEMBL28479499 | 0.80 | NPC1 (0.57) | MEN1KMT2AMAPK1HTTSMN1; SMN2 | |
| SCHEMBL11121827 | 0.80 | SMN1; SMN2 (0.66) | MEN1KMT2AMAPK1HTTSMN1; SMN2 | |
| SCHEMBL17894439 | 0.79 | HTT (0.57) | MEN1KMT2AMAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550292-A | ANXIOLYTIC AND ANTIDEPRESSANT AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0666840-A1 | BENZYLAMINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-16 | — | — | EP | disclosed |
| WO-1995006630-A1 | BENZYLAMINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-09 | — | — | WO | disclosed |