Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985544 | 0.80 | MEN1 (0.64) | MAPK1GAAKMT2AMEN1HTT | |
| SCHEMBL21634323 | 0.78 | MEN1 (0.65) | MAPK1KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL11121827 | 0.78 | SMN1; SMN2 (0.66) | MAPK1KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL13958937 | 0.77 | BCHE (0.69) | MAPK1GAAKMT2AMEN1MAOB | |
| SCHEMBL21634276 | 0.76 | MEN1 (0.62) | MAPK1KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL13462917 | 0.75 | MAOB (0.60) | MAPK1KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL31533129 | 0.75 | APP (0.70) | MAPK1KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL4697290 | 0.75 | APP (0.70) | MAPK1KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL17894439 | 0.74 | HTT (0.57) | NPC1MAPK1GAAKMT2AMEN1 | |
| SCHEMBL8985605 | 0.73 | MEN1 (0.62) | MAPK1KMT2AMEN1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111960970-B | Antitumor compounds | 中国人民解放军总医院 | 2021-08-20 | — | — | CN | claimed |
| CN-111960970-B | Antitumor compounds | 中国人民解放军总医院 | 2021-08-20 | — | — | CN | disclosed |
| CN-108997172-B | Antitumor compounds | 中国人民解放军总医院 | 2020-12-15 | — | — | CN | disclosed |
| CN-111960970-A | Antitumor compounds | 中国人民解放军总医院 | 2020-11-20 | — | — | CN | disclosed |
| CN-111960985-A | Antitumor compounds | 中国人民解放军总医院 | 2020-11-20 | — | — | CN | disclosed |
| CN-111892516-A | Antitumor compounds | 中国人民解放军总医院 | 2020-11-06 | — | — | CN | disclosed |
| CN-111892517-A | Antitumor compounds | 中国人民解放军总医院 | 2020-11-06 | — | — | CN | disclosed |