Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9117138 | 0.80 | BCHE (0.52) | MEN1KMT2ACYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL27582483 | 0.79 | CARM1 (0.58) | MEN1KMT2ATP53CYP3A4CYP2C9 | |
| SCHEMBL20324949 | 0.79 | GAA (0.54) | MEN1KMT2ATP53CYP3A4CYP2D6 | |
| SCHEMBL5646043 | 0.77 | ENPP2 (0.62) | KMT2ACYP3A4CYP2C9CYP2C19ENPP2 | |
| SCHEMBL3423780 | 0.76 | CYP1A2 (0.55) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL30933651 | 0.76 | HTR2C (0.53) | MEN1KMT2ALMNAHTT | |
| SCHEMBL20324336 | 0.76 | GAA (0.56) | MEN1KMT2ATP53GAALMNA | |
| SCHEMBL27702461 | 0.74 | CARM1 (0.64) | KMT2ACYP3A4CYP2C9CYP2C19ENPP2 | |
| SCHEMBL6509968 | 0.74 | HTR2C (0.57) | SLC1A5 | |
| SCHEMBL20324364 | 0.73 | MEN1 (0.58) | MEN1KMT2ATP53CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550292-A | ANXIOLYTIC AND ANTIDEPRESSANT AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |