Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.64 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.64 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28133711 | 0.81 | HRH3 (0.50) | HRH3HRH4CYP1A2CYP2D6TAAR1 | |
| Pyridine SCHEMBL28192678 | 0.80 | HRH3 (0.49) | HRH3HRH4TAAR1 | |
| Niacin SCHEMBL28160298 | 0.79 | GAA (0.57) | HRH3HRH4TAAR1NAPRTTBXAS1 | |
| SCHEMBL20117842 | 0.79 | HRH3 (0.55) | HRH3HRH4CYP11B1CYP11B2TAAR1 | |
| SCHEMBL727185 | 0.77 | CYP1A2 (0.62) | HRH3HRH4MMP2CYP1A2CYP2D6 | |
| SCHEMBL1108477 | 0.76 | TAAR1 (0.50) | HRH3TAAR1 | |
| Hydrochloric Acid SCHEMBL27287864 | 0.74 | TAAR1 (0.48) | HRH3TAAR1 | |
| SCHEMBL27784844 | 0.74 | HRH3 (0.40) | HRH3HRH4CYP11B1CYP11B2TAAR1 | |
| SCHEMBL31688985 | 0.73 | TAAR1 (0.68) | HRH3HRH4MMP2CYP1A2CYP2D6 | |
| SCHEMBL6168636 | 0.73 | TAAR1 (0.68) | HRH3HRH4MMP2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220024869-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF KANSAS | 2022-01-27 | — | — | US | disclosed |
| US-10975030-B2 | Grp94 selective inhibitors and uses thereof | UNIVERSITY OF KANSAS (US) | 2021-04-13 | — | — | US | disclosed |
| US-10975030-B2 | Grp94 selective inhibitors and uses thereof | UNIVERSITY OF KANSAS (US) | 2021-04-13 | — | — | US | disclosed |
| US-20200071271-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF SOUTH FLORIDA | 2020-03-05 | — | — | US | disclosed |
| US-20200071271-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF SOUTH FLORIDA | 2020-03-05 | — | — | US | disclosed |
| CN-105980603-B | The forming method of etching solution, bulking liquor and thin copper film | MEC股份有限公司 | 2019-11-22 | — | — | CN | disclosed |
| CN-109956942-A | Tryptamines ketones derivant and application thereof | 上海翔锦生物科技有限公司 | 2019-07-02 | — | — | CN | disclosed |
| CN-107112587-B | Solid state secondary battery, solid electrolyte composition, battery electrode sheet | 富士胶片株式会社 | 2019-03-19 | — | — | CN | disclosed |
| WO-2018081814-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF KANSAS (US) | 2018-05-03 | — | — | WO | disclosed |
| CN-107208279-A | The forming method of etching solution, bulking liquor and thin copper film | MEC股份有限公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-107112587-A | Solid state secondary battery, solid electrolyte composition and battery electrode sheet and battery electrode sheet and the manufacture method of solid state secondary battery for the solid state secondary battery | 富士胶片株式会社 | 2017-08-29 | — | — | CN | disclosed |
| CN-105980603-A | Etching liquid, replenishing liquid, and method for forming copper wiring | MEC股份有限公司 | 2016-09-28 | — | — | CN | disclosed |
| EP-0717311-A1 | Photographic elements comprising contrast promoting agents | SUN CHEMICAL CORPORATION (US) | 1996-06-19 | — | — | EP | disclosed |
| US-5451486-A | Silver halide photographic film with nucleation agent | SUN CHEMICAL CORPORATION (US) | 1995-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071271-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | GRPR, HSP90B1, HSPE1 | HRH3 2520/4885HRH4 1815/4885MMP2 752/4885 |
| US-20220024869-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | GRPR, HSP90B1, HSPE1 | HRH3 2520/4885HRH4 1815/4885MMP2 752/4885 |
| US-10975030-B2 | Grp94 selective inhibitors and uses thereof | GRPR, HSP90B1, HSPE1 | HRH3 2520/4885HRH4 1815/4885MMP2 752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.