Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGMT | P16455 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28399049 | 0.74 | HRH3 (0.52) | HRH3TAAR1 | |
| SCHEMBL8986293 | 0.74 | HRH3 (0.64) | HRH3HRH4TAAR1CYP11B1CYP11B2 | |
| SCHEMBL4731 | 0.73 | CALM1 (0.48) | HRH3TACR1SLC6A4KCNH2TAAR1 | |
| SCHEMBL20117842 | 0.71 | HRH3 (0.55) | HRH3HRH4TAAR1CYP11B1CYP11B2 | |
| SCHEMBL79201 | 0.69 | MAOA (0.47) | ABL1SRC | |
| SCHEMBL6420054 | 0.68 | PDE10A (0.43) | — | |
| SCHEMBL1108477 | 0.68 | TAAR1 (0.50) | HRH3TAAR1SMN1; SMN2HCAR2 | |
| SCHEMBL27667122 | 0.67 | CYP11B1 (0.42) | HRH3CYP11B1CYP11B2SMN1; SMN2HTT | |
| Pyridine SCHEMBL28133711 | 0.67 | HRH3 (0.50) | HRH3HRH4TAAR1SMN1; SMN2MAPT | |
| SCHEMBL30675676 | 0.67 | EGFR (0.39) | HRH3SMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101591281-A | Phosphonate compounds having immunomodulatory activity | GILEAD SCIENCES INC (US) | 2009-12-02 | — | — | CN | disclosed |