Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | MASP2 | O00187 | 5/20 | 0.36 |
| ▸ | F2 | P00734 | 7/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306243 | 0.80 | KDM1A (0.36) | SLC6A3 | |
| SCHEMBL3547216 | 0.75 | NPC1 (0.40) | — | |
| SCHEMBL3547219 | 0.75 | NPC1 (0.40) | — | |
| SCHEMBL7359958 | 0.73 | MAPK1 (0.36) | — | |
| SCHEMBL22152561 | 0.73 | MAPK1 (0.36) | — | |
| SCHEMBL7379626 | 0.73 | MAPK1 (0.36) | — | |
| SCHEMBL28466500 | 0.73 | GFER (0.40) | SCN9ASCN3A | |
| SCHEMBL27756721 | 0.73 | HDAC2 (0.53) | MASP2F2 | |
| SCHEMBL21707962 | 0.72 | SLC6A3 (0.38) | SLC6A2SCN9ASCN3ASCN5ASLC6A3 | |
| SCHEMBL5459217 | 0.72 | GFER (0.38) | SCN9ASCN3ASCN5ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574055-A | COGNITIVE AND NEURODEGENERATIVE DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1996-11-12 | — | — | US | disclosed |