Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986416 | 0.80 | SLC6A2 (0.37) | SLC6A3 | |
| SCHEMBL27870985 | 0.72 | HDAC2 (0.33) | — | |
| SCHEMBL28825883 | 0.72 | HDAC2 (0.33) | — | |
| SCHEMBL7303971 | 0.69 | SLC18A3 (0.42) | KDM1AP2RY14NAMPTNR1H2 | |
| SCHEMBL8315816 | 0.69 | MEN1 (0.32) | — | |
| SCHEMBL3547219 | 0.68 | NPC1 (0.40) | NAMPTHRH3NR1H2 | |
| SCHEMBL3547216 | 0.68 | NPC1 (0.40) | NAMPTHRH3NR1H2 | |
| SCHEMBL8315133 | 0.68 | GAA (0.33) | SLC6A3 | |
| SCHEMBL22471554 | 0.67 | CHRM2 (0.56) | NAMPTHRH3NR1H2 | |
| SCHEMBL15378924 | 0.67 | CHRM2 (0.56) | NAMPTHRH3NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657440-B1 | Oxazolidine-2-one derivatives as MAO inhibitors | HOFFMANN LA ROCHE (CH) | 2000-04-05 | — | — | EP | disclosed |
| EP-0657440-A1 | Oxazolidine-2-one derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1995-06-14 | — | — | EP | disclosed |