Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11802985 | 0.72 | CYP2C9 (0.39) | KMT2AALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL6547925 | 0.71 | ALDH1A1 (0.45) | KMT2AALDH1A1TSHRAKR1C3MAPT | |
| SCHEMBL6547922 | 0.71 | ALDH1A1 (0.45) | KMT2AALDH1A1TSHRAKR1C3MAPT | |
| SCHEMBL11682473 | 0.70 | CYP3A4 (0.49) | CYP19A1KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL11298113 | 0.70 | AKR1C3 (0.42) | CYP19A1CYP11B2KMT2AMEN1AKR1C3 | |
| SCHEMBL8986568 | 0.69 | CYP19A1 (0.61) | CYP19A1CYP11B2KMT2AMEN1KIF11 | |
| SCHEMBL812727 | 0.69 | CYP19A1 (0.61) | CYP19A1CYP11B2KMT2AMEN1KIF11 | |
| Phosphine SCHEMBL11447782 | 0.69 | AKR1C3 (0.48) | KMT2AMEN1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL28255319 | 0.69 | CYP19A1 (0.55) | CYP19A1CYP11B2KMT2AMEN1ALDH1A1 | |
| SCHEMBL9168210 | 0.69 | KDM4E (0.41) | CYP19A1CYP11B2ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541331-A | Processes for producing α-pyridyl carbinols | REILLY INDUSTRIES, INC. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0641322-A1 | PROCESSES FOR PRODUCING $g(a)-PYRIDYL CARBINOLS | REILLY INDUSTRIES, INC. (US) | 1995-03-08 | — | — | EP | disclosed |
| WO-1992019596-A2 | PROCESSES FOR PRODUCING α-PYRIDYL CARBINOLS | REILLY INDUSTRIES, INC. (US) | 1992-11-12 | — | — | WO | disclosed |