Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630824 | 0.89 | KDM4E (0.48) | KDM4ECYP19A1RAB9ACYP2C19MAOB | |
| SCHEMBL4630827 | 0.89 | KDM4E (0.48) | KDM4ECYP19A1RAB9ACYP2C19MAOB | |
| SCHEMBL4631552 | 0.74 | RELA (0.61) | KDM4ERAB9ACYP2C19CYP1B1NPC1 | |
| SCHEMBL4631554 | 0.74 | RELA (0.61) | KDM4ERAB9ACYP2C19CYP1B1NPC1 | |
| SCHEMBL3906030 | 0.73 | KDM4E (0.57) | KDM4ECYP2C19MAPTALDH1A1 | |
| SCHEMBL3906029 | 0.73 | KDM4E (0.57) | KDM4ECYP2C19MAPTALDH1A1 | |
| SCHEMBL9448703 | 0.72 | RELA (0.59) | KDM4ERAB9ACYP1B1NPC1MAPT | |
| SCHEMBL9448701 | 0.72 | RELA (0.59) | KDM4ERAB9ACYP1B1NPC1MAPT | |
| SCHEMBL8986568 | 0.72 | CYP19A1 (0.61) | USP2CYP11B2CYP11B1CYP19A1RAB9A | |
| SCHEMBL812727 | 0.72 | CYP19A1 (0.61) | USP2CYP11B2CYP11B1CYP19A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641322-A1 | PROCESSES FOR PRODUCING $g(a)-PYRIDYL CARBINOLS | REILLY INDUSTRIES, INC. (US) | 1995-03-08 | — | — | EP | disclosed |
| WO-1992019596-A2 | PROCESSES FOR PRODUCING α-PYRIDYL CARBINOLS | REILLY INDUSTRIES, INC. (US) | 1992-11-12 | — | — | WO | disclosed |